Low-variance RNAs identify Parkinson's disease molecular signature in blood

Author:

Chikina Maria D.1,Gerald Christophe P.1,Li Xianting1,Ge Yongchao1,Pincas Hanna1,Nair Venugopalan D.1,Wong Aaron K.2,Krishnan Arjun2,Troyanskaya Olga G.2,Raymond Deborah3,Saunders-Pullman Rachel3,Bressman Susan B.3,Yue Zhenyu1,Sealfon Stuart C.1

Affiliation:

1. Departments of Neurology and Neuroscience; Icahn School of Medicine at Mount Sinai; New York New York USA

2. Department of Computer Science; Lewis-Sigler Institute for Integrative Genomics, Princeton University; Princeton New Jersey USA

3. Department of Neurology; Mount Sinai Beth Israel; New York New York USA

Funder

Michael J. Fox Foundation

National Institutes of Health

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Reference61 articles.

1. Accuracy of diagnosis in patients with presumed Parkinson's disease;Meara;Age Ageing,1999

2. What genetics tells us about the causes and mechanisms of Parkinson's disease;Corti;Physiol Rev,2011

3. Premotor biomarkers for Parkinson's disease-a promising direction of research;Haas;Transl Neurodegener,2012

4. Association of cerebrospinal fluid beta-amyloid 1-42, T-tau, P-tau181, and alpha-synuclein levels with clinical features of drug-naive patients with early Parkinson disease;Kang;JAMA Neurol,2013

5. A molecular signature in blood identifies early Parkinson's disease;Molochnikov;Mol Neurodegener,2012

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