Bimetallic CoCeO2 oxide nanoparticles: An efficient and reusable heterogeneous catalyst for the preparation of 2‐amino‐3‐cyano‐4H‐pyran derivatives

Abstract

AbstractCoCeO2 NPs were successfully synthesized and confirmed using x‐ray diffraction (XRD), field emission scanning electron microscopy (FESEM), and high‐resolution transmission electron microscopy (HRTEM) techniques. The catalytic performance of the synthesized CoCeO2 NPs catalyst was examined during the one‐pot multicomponent synthesis of biologically significant 2‐amino‐3‐cyano‐4H‐pyran derivatives. The reaction was easily accomplished using a one‐pot, three‐component reaction of dimedone, aryl aldehydes, and malononitrile in ethanol under reflux, with excellent yields and a short reaction time. The current catalytic system is more appealing because of its simple reaction conditions, uncomplicated product isolation, economic feasibility, and reusability of the catalyst free from significant loss of activity. This process offers an effective strategy for the synthesis of 2‐amino‐3‐cyano‐4H‐pyran derivatives.