Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines-Reference-Cited by-同舟云学术

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Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines

Published:2009-07 Issue:1 Volume:220 Page:214-221
ISSN:0021-9541
Container-title:Journal of Cellular Physiology
language:en
Short-container-title:J. Cell. Physiol.

Author:

Ulivi Paola,Arienti Chiara,Amadori Dino,Fabbri Francesco,Carloni Silvia,Tesei Anna,Vannini Ivan,Silvestrini Rosella,Zoli Wainer

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcp.21753/fullpdf

Reference26 articles.

1. Pancreatic cancer biology and genetics;Bardeesy;Nat Rev Cancer,2002

2. MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells;Boucher;J Cell Biochem,2000

3. Farnesyltransferase inhibitors: An overview of the results of preclinical and clinical investigations;Brunner;Cancer Res,2003

4. Sorafenib triggers antiproliferative and pro-apoptotic signals in human esophageal adenocarcinoma cells;Delgado;Dig Dis Sci,2008

5. Pharmacologic inhibition of RAF → MEK → ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1;Gysin;Cancer Res,2005

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