NF023 binding to XIAP-BIR1: Searching drugs for regulation of the NF-κB pathway
Author:
Affiliation:
1. Dipartimento Di Bioscienze; Università Di Milano; I-20133 Italy
2. Biophysics Institute, National Research Council; Milano I-20133 Italy
Funder
CARIPLO Foundation Project
Publisher
Wiley
Subject
Molecular Biology,Biochemistry,Structural Biology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/prot.24766/fullpdf
Reference34 articles.
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4. IAP proteins: blocking the road to death's door;Salvesen;Nat Rev Mol Cell Biol,2002
5. IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis;Gyrd-Hansen;Nat Cell Biol,2008
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1. Structure-based identification of a new IAP-targeting compound that induces cancer cell death inducing NF-κB pathway;Computational and Structural Biotechnology Journal;2021
2. Computational and Experimental Characterization of NF023, A Candidate Anticancer Compound Inhibiting cIAP2/TRAF2 Assembly;Journal of Chemical Information and Modeling;2020-08-21
3. Regulation of Cell Death and Immunity by XIAP;Cold Spring Harbor Perspectives in Biology;2019-12-16
4. Structure‐Activity Relationship of NF023 Derivatives Binding to XIAP‐BIR1;ChemistryOpen;2019-04
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