Population Pharmacokinetics Modeling of Unbound Efavirenz, Atazanavir, and Ritonavir in HIV‐Infected Subjects With Aging Biomarkers

Author:

Dumond JB1,Chen J1,Cottrell M1,Trezza CR1,Prince HMA2,Sykes C1,Torrice C3,White N1,Malone S1,Wang R1,Patterson KB2,Sharpless NE3,Forrest A1

Affiliation:

1. UNC Eshelman School of PharmacyUniversity of North Carolina at Chapel HillChapel Hill North Carolina USA

2. School of MedicineUniversity of North Carolina at Chapel HillChapel Hill North Carolina USA

3. Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel HillChapel Hill North Carolina USA

Funder

Society of Infectious Disease Pharmacists Young Investigator Research Award

UNC Center for AIDS Research

Publisher

Wiley

Subject

Pharmacology (medical),Modelling and Simulation

Reference45 articles.

1. Pharmacokinetics and drug metabolism in the elderly

2. Changes in plasma protein binding have little clinical relevance

3. Free Drug Metabolic Clearance in Elderly People

4. Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV‐1‐infected adults and adolescents. February 12 2013 Department of Health and Human Services. .

5. Aging and Infectious Diseases: Workshop on HIV Infection and Aging: What Is Known and Future Research Directions

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