Gastrointestinal dysfunction in patients and mice expressing the autism‐associated R451C mutation in neuroligin‐3

Author:

Hosie Suzanne1ORCID,Ellis Melina2,Swaminathan Mathusi2,Ramalhosa Fatima3,Seger Gracia O.2,Balasuriya Gayathri K.1ORCID,Gillberg Christopher4ORCID,Råstam Maria45ORCID,Churilov Leonid67,McKeown Sonja J.8ORCID,Yalcinkaya Nalzi9,Urvil Petri9,Savidge Tor9,Bell Carolyn A.10,Bodin Oonagh10,Wood Jen10,Franks Ashley E.10ORCID,Bornstein Joel C.2ORCID,Hill‐Yardin Elisa L.12

Affiliation:

1. School of Health and Biomedical Sciences RMIT University Bundoora VIC Australia

2. Department of Physiology The University of Melbourne Parkville VIC Australia

3. Life and Health Sciences Research Institute, University of Minho Braga Portugal

4. Gillberg Neuropsychiatry Centre Institute of Neuroscience and Physiology, University of Gothenburg Göteborg Sweden

5. Department of Clinical Sciences Lund Child and Adolescent Psychiatry, Lund University Lund Sweden

6. School of Science Cluster RMIT University, Melbourne City Campus Melbourne VIC Australia

7. Florey Institute of Neuroscience and Mental Health Heidelberg VIC Australia

8. Cancer Program, Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology Monash University Clayton VIC Australia

9. Texas Children's Microbiome Center, Texas Children's Hospital and Department of Pathology and Immunology Baylor College of Medicine Houston Texas

10. La Trobe University, Department of Physiology, Anatomy & Microbiology School of Life Sciences Bundoora VIC Australia

Funder

Congressionally Directed Medical Research Programs

National Health and Medical Research Council

National Institute of Allergy and Infectious Diseases

National Institute of Diabetes and Digestive and Kidney Diseases

Royal Melbourne Hospital Neuroscience Foundation

Publisher

Wiley

Subject

Genetics(clinical),Clinical Neurology,General Neuroscience

Reference49 articles.

1. Diagnostic and Statistical Manual of Mental Disorders

2. A sexually dimorphic effect of cholera toxin: rapid changes in colonic motility mediated via a 5-HT3receptor-dependent pathway in female C57Bl/6 mice

3. Alfaxalone, pentobarbital and diazepam potentiate gamma‐aminobutyric acid‐induced depolarizations in single myenteric neurons of guinea pig intestine;Bertrand P. P.;The Journal of Pharmacology and Experimental Therapeutics,1992

4. The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders

5. A synaptic trek to autism

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