Immune reconstitution inflammatory syndrome‐associated lymphoma: A retrospective Brazilian cohort-Reference-Cited by-同舟云学术

Immune reconstitution inflammatory syndrome‐associated lymphoma: A retrospective Brazilian cohort

Published:2023-12-20 Issue: Volume: Page:
ISSN:2688-6146
Container-title:eJHaem
language:en
Short-container-title:eJHaem

Author:

Vargas Juliano Cordova¹²³^ORCID,Cecyn Karin Zattar¹,de Oliveira Marques Mariana¹⁴^ORCID,Pereira Juliana⁵,Tobias Braga Walter M.⁶,Hamerschlak Nelson²⁷,Tabacof Jacques⁸,de Liz Caina D.⁹,Abdo André⁴,Ferreira Paulo Roberto Abrão¹⁰,Colleoni Gisele W. Braga¹,Baiocchi Otavio C. G.¹⁴

Affiliation:

1. Department of Clinical and Experimental Oncology Federal University of São Paulo São Paulo SP Brazil

2. Department of Hematology Américas Oncologia e Hematologia São Paulo SP Brazil

3. School of Medicine Centro Universitário São Camilo São Paulo SP Brazil

4. Department of Hematology Hospital Alemão Oswaldo Cruz São Paulo SP Brazil

5. Department of Clinical and Hematology São Paulo State Cancer Institute University of São Paulo São Paulo SP Brazil

6. Department of Hematology Emílio Ribas Institute of Infectious Diseases São Paulo SP Brazil

7. Department of Hematology Hospital Israelita Albert Einstein São Paulo SP Brazil

8. Centro Paulista de Oncologia São Paulo SP Brazil

9. Department of Hematology Hospital Sírio Libanês São Paulo SP Brazil

10. Division of Infectious Disease Escola Paulista de Medicina Federal University of São Paulo São Paulo SP Brazil

Abstract

AbstractAfter initiating combined antiretroviral therapy (cART), individuals with human immunodeficiency virus (HIV) may develop Hodgkin/non‐Hodgkin lymphoma due to immune reconstitution inflammatory syndrome (IRIS). This retrospective cohort study evaluated the incidence, clinical features and prognosis of IRIS‐associated lymphomas in Brazilian patients. Incidence in 2000–2019 was 9.8% (27/276 patients with HIV and lymphoma; viral load drop >1 log). Time between HIV diagnosis and cART initiation was <1 year in 70.3% of cases. Time between cART initiation and lymphoma diagnosis was <3 months in 11 cases and 3–6 months in 16 cases. Overall and progression‐free survival rates were similar between cases of non‐IRIS‐associated lymphoma and IRIS‐associated lymphoma.

Publisher

Wiley

Subject

General Earth and Planetary Sciences

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jha2.835

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