Structure-Activity Relationships of Oxygenated Morphinans. I. 4-Mono- and 3,4-dimethoxy-N-methylmorphinans and -N-methyl-morphinan-6-ones with unusually high antinociceptive potency. Preliminary communication

Author:

Jacobson Arthur E.,Hsu Fu-Lian,Rozwadowska Maria D.,Schmidhammer Helmut,Atwell Louise,Brossi Arnold,Medzihradsky Fedor

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Biochemistry,Catalysis

Reference20 articles.

1. Deoxymorphines: role of the phenolic hydroxyl in antinociception and opiate receptor interactions

2. & in: ?Synthetic Analgesics. Part II (A) Morphinans,? Pergamon Press, N. Y. 1966.

3. & in: ?Analgetics,? ed., Acad. Press, New York 1965, pp. 123-174.

4. & in: ?Medicinal Chemistry,? Part II, 3rd Edition, ed., Wiley-Interscience, New York 1970, pp. 1327-1349.

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