A rare presentation of primary cardiac myxofibrosarcoma: Case report and literature review

Author:

Soltani Sepideh1ORCID,Garousi Maryam1ORCID,Mirzaee Elahe1ORCID,Koolaji Sogol2,Nazari Hengameh3,Emami Sepideh4,Zare Mehrjardi Ali5,Arefpour Amir Mohammad1

Affiliation:

1. Department of Radiation Oncology, School of Medicine Iran University of Medical Sciences Tehran Iran

2. Non‐communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran Iran

3. Department of Radiology Isfahan University of Medical Sciences Isfahan Iran

4. Department of Cardiology, Firoozgar Hospital, School of Medicine Iran University of Medical Sciences Tehran Iran

5. Department of Pathology, Firoozgar Hospital Iran University of Medical Sciences Tehran Iran

Abstract

AbstractBackgroundPrimary cardiac myxofibrosarcoma is a rare and aggressive malignancy, with the majority of approaching strategies relying on case reports. This article provides insights into its diagnosis and treatment.Case PresentationThis paper presents the case of a 40‐year‐old man with sudden onset hemoptysis, leading to the diagnosis of primary cardiac myxofibrosarcoma. Treatment involved open‐heart surgery to excise the left atrium tumor, followed by 6 cycles of adjuvant chemotherapy. Unfortunately, brain metastasis developed, leading to the patient's death 1 year after initial diagnosis.ConclusionPrimary cardiac myxofibrosarcoma remains a clinical challenge with an unfavorable prognosis. Early diagnosis through advanced imaging is crucial, and research is needed to explore innovative treatments. This case underscores the complexities of managing this rare cardiac malignancy and highlights the necessity for ongoing investigations to enhance patient outcomes.

Publisher

Wiley

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