HPMA Copolymer Conjugates of DOX and Mitomycin C for Combination Therapy: Physicochemical Characterization, Cytotoxic Effects, Combination Index Analysis, and Anti-Tumor Efficacy-Reference-Cited by-同舟云学术

HPMA Copolymer Conjugates of DOX and Mitomycin C for Combination Therapy: Physicochemical Characterization, Cytotoxic Effects, Combination Index Analysis, and Anti-Tumor Efficacy

Published:2013-09-12 Issue:12 Volume:13 Page:1648-1660
ISSN:1616-5187
Container-title:Macromolecular Bioscience
language:en
Short-container-title:Macromol. Biosci.

Author:

Kostková Hana¹,Etrych Tomáš¹,Říhová Blanka²,Kostka Libor¹,Starovoytová Larisa¹,Kovář Marek²,Ulbrich Karel¹

Affiliation:

1. Institute of Macromolecular Chemistry Academy of Sciences of the Czech Republic; v.v.i., Heyrovsky Sq. 2 162 06 Prague 6 Czech Republic

2. Institute of Microbiology; Academy of Sciences of the Czech Republic; v.v.i, Vídeňská 1083 142 20 Prague 4 Czech Republic

Funder

Grant Agency of the Czech Republic

Ministry of Education, Youth and Sports of the Czech Republic

Publisher

Wiley

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering,Biotechnology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/mabi.201300288/fullpdf

Reference42 articles.

1. Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine

2. Cytostatic and immunomobilizing activities of polymer-bound drugs: experimental and first clinical data

3. Clinical experience with anthracycline antibiotics–HPMA copolymer–human immunoglobulin conjugates

4. New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties

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