Polymeric Micelles Loading Proteins through Concurrent Ion Complexation and pH‐Cleavable Covalent Bonding for In Vivo Delivery

Author:

Tao Anqi1,Huang George Lo1,Igarashi Kazunori2,Hong Taehun1,Liao Suiyang3,Stellacci Francesco34,Matsumoto Yu2,Yamasoba Tatsuya2,Kataoka Kazunori56,Cabral Horacio1ORCID

Affiliation:

1. Department of Bioengineering, Graduate School of EngineeringThe University of Tokyo 7‐3‐1 Hongo, Bunkyo‐ku Tokyo 113‐0033 Japan

2. Department of Otorhinolaryngology and Head and Neck SurgeryGraduate School of Medicine and Faculty of MedicineThe University of Tokyo 7‐3‐1 Hongo, Bunkyo‐ku Tokyo 113‐0033 Japan

3. Institute of MaterialsÉcole Polytechnique Fédérale de Lausanne 1015 Lausanne Switzerland

4. Interfaculty Bioengineering InstituteÉcole Polytechnique Fédérale de Lausanne 1015 Lausanne Switzerland

5. Innovation Center of NanoMedicine (iCONM)Kawasaki Institute of Industrial Promotion 3‐25‐14 Tonomachi, Kawasaki‐ku Kawasaki 210‐0821 Japan

6. Institute for Future InitiativesThe University of Tokyo 7‐3‐1 Hongo, Bunkyo‐ku Tokyo 113‐0033 Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering,Biotechnology

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