pRb2/p130 Localizes to the Cytoplasm in Diffuse Gastric Cancer

Author:

Cito Letizia1,Indovina Paola23,Forte Iris Maria1,Pentimalli Francesca1,Di Marzo Domenico1,Somma Pasquale4,Barone Daniela1,Penon Antonella2,Penon Danila5,Ceccherini Elisa2,Micheli Pietro4,Saragoni Luca6,Di Domenico Marina37,Feola Antonia78,Roviello Franco9,Mattioli Eliseo210,Giordano Giovan Giacomo8,Giordano Antonio123

Affiliation:

1. Oncology Research Center of Mercogliano (CROM); Istituto Nazionale per lo studio e la cura dei tumori “Fondazione Giovanni Pascale”-IRCCS; Naples Italy

2. Department of Medicine; Surgery and Neuroscience, University of Siena and Istituto Toscano Tumori (ITT); Siena Italy

3. Sbarro Institute for Cancer Research and Molecular Medicine; Center for Biotechnology; Temple University; Philadelphia Pennsylvania

4. Azienda Ospedaliera dei Colli-Pathology section; Naples Italy

5. Department of Biochemistry and Medical Biotechnology; University of Naples Federico II; Naples Italy

6. Pathology Division; Morgagni-Pierantoni Hospital; Forlì Italy

7. Department of Biochemistry; Biophysics and General Pathology; Second University of Naples; Naples Italy

8. Department of Biology; University Federico II of Naples; Naples Italy

9. Department of Medicine; Surgery and Neuroscience, Unit of Surgical Oncology; University of Siena; Siena Italy

10. Division of Anatomic Pathology; “Madonna delle Grazie” Hospital; Matera Italy

Funder

Zegar Family Foundation (AG)

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference41 articles.

1. Genomic structure of the human retinoblastoma-related Rb2/p130 gene;Baldi;Proc Natl Acad Sci USA,1996

2. The RB2/p130 gene product is a nuclear protein whose phosphorylation is cell cycle regulated;Baldi;J Cell Biochem,1995

3. Loss of pRb2/p130 expression is associated with unfavorable clinical outcome in lung cancer;Caputi;Clin Cancer Res,2002

4. High expressions of galectin-1 and VEGF are associated with poor prognosis in gastric cancer patients;Chen;Tumour Biol,2014

5. Histotype-based prognostic classification of gastric cancer;Chiaravalli;World J Gastroenterol,2012

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