Affiliation:
1. China National Biological Group‐Virogin Biotech (Shanghai) Ltd (CNBG‐Virogin) 201802 Shanghai China
2. Virogin Biotech (Shanghai) Ltd. 201802 Shanghai China
3. Virogin Biotech (Canada) Ltd. V6V1A8 Richmond Canada
4. China National Biotech Group (CNBG) 100024 Beijing China
Abstract
AbstractNucleic acid drugs can treat diseases caused by defective or abnormal genes. Herein, the mechanism of non‐viral vectors for nucleic acid drug delivery is described. This review introduce non‐viral vectors for nucleic acid drug delivery, including the nucleic acid‐carrier conjugate, proteins and peptides‐based nanoparticles, polysaccharides, and other biological macromolecules‐based nanoparticles consisting of lipid nanoparticles, synthetic polymers‐based nanoparticles, inorganic nanoparticles, and organic–inorganic hybrid nanoparticles. Finally, the challenges and prospects of non‐viral vectors for nucleic acid drug delivery are discussed.
Subject
Pharmacology (medical),Biochemistry (medical),Genetics (clinical),Pharmaceutical Science,Pharmacology,Medicine (miscellaneous)
Cited by
3 articles.
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