Comparative Study between the 3D‐Liver Spheroid Models Developed from HepG2 and Immortalized Hepatocyte‐Like Cells with Primary Hepatic Stellate Coculture for Drug Metabolism Analysis and Anticancer Drug Screening-Reference-Cited by-同舟云学术

Comparative Study between the 3D‐Liver Spheroid Models Developed from HepG2 and Immortalized Hepatocyte‐Like Cells with Primary Hepatic Stellate Coculture for Drug Metabolism Analysis and Anticancer Drug Screening

Published:2022-12-14 Issue:2 Volume:6 Page:2200169
ISSN:2366-3987
Container-title:Advanced Therapeutics
language:en
Short-container-title:Advanced Therapeutics

Author:

Sae‐be Arunsajee¹,Wiwatpanit Teerawat²,Varatthan Thaveechai²,Namporn Thanaphon¹,Laungkulldej Sasiwat¹,Thiabma Ratthiya²,Jaiboonma Atchara²,Sa‐ngiamsuntorn Khanit³,Elson Daniel⁴,Porter Alexandra E.⁵,Sathirakul Korbtham¹,Hongeng Suradej⁶,Ruenraroengsak Pakatip¹^ORCID

Affiliation:

1. Department of Pharmacy Faculty of Pharmacy Mahidol University 447 Sri‐Ayutthaya Rd Rajathevi Bangkok 10400 Thailand

2. National Center for Genetic Engineering and Biotechnology (BIOTEC) National Science and Technology Development Agency (NSTDA) Pathum Thani 10200 Thailand

3. Department of Biochemistry Faculty of Pharmacy Mahidol University 447 Sri‐Ayutthaya Rd Rajathevi Bangkok 10400 Thailand

4. Department of Surgery and Cancer Imperial College London South Kensington Campus Exhibition Road London SW7 2AZ UK

5. Department of Materials and London Centre for Nanotechnology Imperial College London Exhibition Road London SW7 2AZ UK

6. Department of Pediatrics Faculty of Medicine Ramathibodi Hospital Mahidol University Rama VI Rd Rajathevi Bangkok 10400 Thailand

Funder

Mahidol University

Thailand Science Research and Innovation

National Research Council of Thailand

Publisher

Wiley

Subject

Pharmacology (medical),Biochemistry (medical),Genetics (clinical),Pharmaceutical Science,Pharmacology,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/adtp.202200169

Reference68 articles.

1. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

2. A global view of hepatocellular carcinoma: trends, risk, prevention and management

3. Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models

4. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

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