The Role of Extracellular Vesicles in Tumor Therapy and Imaging

Abstract

AbstractCancer is a major disease that poses a serious threat to human health. The therapy and imaging methods of cancer are still widely studied as hotspots for numerous researchers. In particular, the rapid development of nanoscience and technology provide new strategies for tumor therapy and imaging. Extracellular vesicles (EVs) are suggested as potential tumor therapy and imaging tools due to the low immunogenicity, good biocompatibility, high safety, and their natural ability to penetrate biological barriers. This review summarizes the applications of EVs originating from different sources in tumor therapy and imaging, and proposes the advantages and remaining limitations of EVs in this field. EVs from different sources show unique strengths and delivery potentials in tumor‐related research. By focusing on the selection of suitable sources of EVs for therapy and imaging under different conditions, this work expects to provide more knowledge on the potential of EVs in the medical application in the future.