GermlineSMARCE1mutations predispose to both spinal and cranial clear cell meningiomas

Author:

Smith Miriam J1,Wallace Andrew J1,Bennett Chris2,Hasselblatt Martin3,Elert-Dobkowska Ewelina45,Evans Linton T6,Hickey William F7,van Hoff Jack8,Bauer David8,Lee Amy9,Hevner Robert F10,Beetz Christian4,du Plessis Daniel11,Kilday John-Paul12,Newman William G1,Evans D Gareth1

Affiliation:

1. Manchester Centre for Genomic Medicine; University of Manchester, Manchester Academic Health Sciences Centre (MAHSC); UK

2. Department of Clinical Genetics; Chapel Allerton Hospital, Leeds Teaching Hospitals NHS Trust; UK

3. Institute of Neuropathology; University Hospital Münster; Germany

4. Institut für Klinische Chemie und Laboratoriumsdiagnostik Universitätsklinikum Jena; Germany

5. Institute of Psychiatry and Neurology; Department of Genetics; Warsaw Poland

6. Section of Neurosurgery; Dartmouth-Hitchcock Medical Center; Lebanon NH USA

7. Department of Pathology; Dartmouth-Hitchcock Medical Center; Lebanon NH USA

8. Pediatric Hematology/Oncology; Dartmouth-Hitchcock Medical Center; Lebanon NH USA

9. Division of Neurosurgery; Seattle Children's Hospital; WA USA

10. Center for Integrative Brain Research; Seattle Children's Research Institute; WA USA

11. Department of Cellular Pathology and Greater Manchester Neurosciences Centre; Salford Royal Hospitals NHS Foundation Trust; UK

12. Children's Brain Tumour Research Network, Department of Haematology/Oncology; Royal Manchester Children's Hospital; UK

Funder

Children's Tumor Foundation

Association for International Cancer Research

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference13 articles.

1. NIH conference. Neurofibromatosis 1 (Recklinghausen disease) and neurofibromatosis 2 (bilateral acoustic neurofibromatosis). An update;Mulvihill;Ann Intern Med,1990

2. Analysis of the neurofibromatosis 2 gene reveals molecular variants of meningioma;Wellenreuther;Am J Pathol,1995

3. Frequent NF2 gene transcript mutations in sporadic meningiomas and vestibular schwannomas;Lekanne Deprez;Am J Hum Genet,1994

4. INI1 mutations in meningiomas at a potential hotspot in exon 9;Schmitz;Br J Cancer,2001

5. SMARCB1 mutations are not a common cause of multiple meningiomas;Hadfield;J Med Genet,2010

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