Versatile and Remotely Controllable Light‐Induced Coagulation of Particles Under Flow in a 2D Channel

Abstract

AbstractOn‐demand switch on/off blood clogging is of paramount importance for the survival of mammals, for example as a quick response to seal damage wounds to minimize their bleeding rate. This mechanism is a complex chain process from initiated red blood cell aggregation at the target location (open wound) that quickly seals on a macroscopic scale the damaged flash. Inspired by nature an on‐demand switchable particle clogging mechanism is developed with high spatial resolution down to micrometer size using light as an external non‐invasive stimulation. Particle clogging can be adjusted on demand strong enough to even withstand pressure‐driven fluid flow, additionally building up walls of aggregated particles, which stop the momentum of big particles under shear. The principle relies on a photosensitive surfactant, which induces under light illumination a long‐ranged lateral attractive phoretic‐osmotic activity of silica microparticles forcing them to aggregate. The strength of aggregation and therefore motion reduction or even stop of the particles against the fluid flow depends on the ratio between the aggregation strength and the velocity of the particles. The aggregation strength can be precisely controlled by the applied light intensity and adjusted particle concentration. Increasing both parameters results in a stronger aggregation tendency.