An Ultrasensitive Ti3C2Tx MXene‐based Soft Contact Lens for Continuous and Nondestructive Intraocular Pressure Monitoring

Author:

Duan Zhongyi1,Yuan Miao2,Liu Zhiduo3,Pei Weihua2ORCID,Jiang Kai4,Li La1ORCID,Shen Guozhen1ORCID

Affiliation:

1. School of Integrated Circuits and Electronics Beijing Institute of Technology Beijing 100081 P. R. China

2. State Key Laboratory of Integrated Optoelectronics Institute of Semiconductors Chinese Academy of Sciences Beijing 100083 P. R. China

3. School of Physics Beijing Institute of Technology Beijing 100081 P. R. China

4. Faculty of Hepato‐Pancreato‐Biliary Surgery Chinese PLA General Hospital Institute of Hepatobiliary Surgery of Chinese PLA & Key Laboratory of Digital Hepatobiliary Surgery Beijing 100853 P. R. China

Abstract

AbstractWearable soft contact lens sensors for continuous and nondestructive intraocular pressure (IOP) monitoring are highly desired as glaucoma and postoperative myopia patients grow, especially as the eyestrain crowd increases. Herein, a smart closed‐loop system is presented that combines a Ti3C2Tx MXene‐based soft contact lens (MX‐CLS) sensor, wireless data transmission units, display, and warning components to realize continuous and nondestructive IOP monitoring/real‐time display. The fabricated MX‐CLS device exhibits an extremely high sensitivity of 7.483 mV mmHg−1, good linearity on silicone eyeballs, excellent stability under long‐term pressure‐release measurement, sufficient transparency with 67.8% transmittance under visible illumination, and superior biocompatibility with no discomfort when putting the MX‐CLS sensor onto the Rabbit eyes. After integrating with the wireless module, users can realize real‐time monitoring and warning of IOP via smartphones, the demonstrated MX‐CLS device together with the IOP monitoring/display system opens up promising platforms for Ti3C2Tx materials as the base for multifunctional contact lens‐based sensors and continuous and nondestructive IOP measurement system.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Publisher

Wiley

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