Preparation and Application of Hemostatic Hydrogels

Author:

Zhou Minyu1ORCID,Lin Xiang2,Wang Li2,Yang Chaoyu3,Yu Yunru2,Zhang Qingfei13ORCID

Affiliation:

1. The First Affiliated Hospital Wenzhou Medical University Wenzhou 325035 China

2. Pharmaceutical Sciences Laboratory Åbo Akademi University Turku 20520 Finland

3. Wenzhou Institute University of Chinese Academy of Sciences Wenzhou Zhejiang 325001 China

Abstract

AbstractHemorrhage remains a critical challenge in various medical settings, necessitating the development of advanced hemostatic materials. Hemostatic hydrogels have emerged as promising solutions to address uncontrolled bleeding due to their unique properties, including biocompatibility, tunable physical characteristics, and exceptional hemostatic capabilities. In this review, a comprehensive overview of the preparation and biomedical applications of hemostatic hydrogels is provided. Particularly, hemostatic hydrogels with various materials and forms are introduced. Additionally, the applications of hemostatic hydrogels in trauma management, surgical procedures, wound care, etc. are summarized. Finally, the limitations and future prospects of hemostatic hydrogels are discussed and evaluated. This review aims to highlight the biomedical applications of hydrogels in hemorrhage management and offer insights into the development of clinically relevant hemostatic materials.

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Biomaterials,Biotechnology,General Materials Science,General Chemistry

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