Intracerebral Injection of Graphene Oxide Nanosheets Mitigates Microglial Activation Without Inducing Acute Neurotoxicity: A Pilot Comparison to Other Nanomaterials

Author:

Portioli Corinne12,Bussy Cyrill134ORCID,Mazza Mariarosa1,Lozano Neus135,Jasim Dhifaf A.13,Prato Maurizio678,Bianco Alberto9,Bentivoglio Marina2,Kostarelos Kostas135ORCID

Affiliation:

1. Nanomedicine Lab School of Health Sciences Faculty of Biology, Medicine and Health The University of Manchester Manchester M13 9PL UK

2. Department of Neurosciences Biomedicine and Movement Sciences University of Verona Verona 37134 Italy

3. National Graphene Institute The University of Manchester Manchester M13 9PL UK

4. Lydia Becker Institute of Immunology and Inflammation Faculty of Biology, Medicine and Health The University of Manchester Manchester M13 9PL UK

5. Catalan Institute of Nanoscience and Nanotechnology (ICN2) and The Barcelona Institute of Science and Technology (BIST) Campus UAB Bellaterra Barcelona 08193 Spain

6. Department of Chemical and Pharmaceutical Sciences University of Trieste Trieste 34127 Italy

7. Center for Cooperative Research in Biomaterials (CIC biomaGUNE) Basque Research and Technology Alliance (BRTA) Paseo de Miramón 182 Donostia‐San Sebastián 20014 Spain

8. Ikerbasque, Basque Foundation for Science Bilbao 48009 Spain

9. CNRS Immunology, Immunopathology and Therapeutic Chemistry UPR3572, ISIS University of Strasbourg Strasbourg 67000 France

Funder

Horizon 2020 Framework Programme

Centre National de la Recherche Scientifique

Centre International de Recherche aux Frontières de la Chimie

Agence Nationale de la Recherche

AXA Research Fund

Ministerio de Economía y Competitividad

Università degli Studi di Trieste

Agencia Estatal de Investigación

Fondazione Cassa di Risparmio di Verona Vicenza Belluno e Ancona

Università degli Studi di Verona

Publisher

Wiley

Subject

Biomaterials,Biotechnology,General Materials Science,General Chemistry

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