Microfluidic In Vitro Platform for (Nano)Safety and (Nano)Drug Efficiency Screening

Author:

Kohl Yvonne1ORCID,Biehl Margit1,Spring Sarah1,Hesler Michelle1,Ogourtsov Vladimir2,Todorovic Miomir2,Owen Joshua3,Elje Elisabeth45,Kopecka Kristina6,Moriones Oscar Hernando78,Bastús Neus G.7,Simon Peter9,Dubaj Tibor9,Rundén‐Pran Elise4,Puntes Victor71011,William Nicola12,Briesen Hagen1,Wagner Sylvia1,Kapur Nikil3,Mariussen Espen4,Nelson Andrew12,Gabelova Alena6,Dusinska Maria4,Velten Thomas1,Knoll Thorsten1

Affiliation:

1. Fraunhofer Institute for Biomedical Engineering IBMT Fraunhofer‐Gesellschaft zur Förderung der angewandten Forschung e.V. Joseph‐von‐Fraunhofer‐Weg 1 Sulzbach 66280 Germany

2. Tyndall National Institute University College Cork Dyke Parade Cork T12 R5CP Ireland

3. Institute of Thermofluids School of Mechanical Engineering University of Leeds Leeds LS2 9JT UK

4. NILU‐Norwegian Institute for Air Research Department for Environmental Chemistry Health Effects Laboratory Instituttveien 18 Kjeller 2007 Norway

5. Faculty of Medicine Institute of Basic Medical Sciences Department of Molecular Medicine University of Oslo Sognsvannsveien 9 Oslo 0372 Norway

6. Department of Nanobiology Cancer Research Institute Biomedical Research Center of the Slovak Academy of Sciences Dubravska cesta 9 Bratislava 84505 Slovakia

7. Institut Català de Nanociència i Nanotecnologia (ICN2) CSIC and BIST Campus UAB, Bellaterra 08193 Barcelona Spain

8. Universitat Autònoma de Barcelona (UAB) Campus UAB, Bellaterra, 08193 Barcelona Spain

9. Institute of Physical Chemistry and Chemical Physics Faculty of Chemical and Food Technology SUT Radlinskeho 9 Bratislava 812 37 Slovakia

10. Vall d'Hebron Institut de Recerca (VHIR) Barcelona 08193 Spain

11. Institució Catalana de Recerca i Estudis Avançats (ICREA) Barcelona 08193 Spain

12. School of Chemistry University of Leeds Leeds LS2 9JT UK

Funder

European Cooperation in Science and Technology

Norges Forskningsråd

Horizon 2020 Framework Programme

Publisher

Wiley

Subject

Biomaterials,Biotechnology,General Materials Science,General Chemistry

Reference105 articles.

1. European Comission Regulation (EC) No 1907/2006 – Registration Evaluation Authorisation and Restriction of Chemicals (REACH) – EU‐OSHA https://osha.europa.eu/de/legislation/directives/regulation-ec-no-1907-2006-of-the-european-parliament-and-of-the-council(accessed: November 2020)

2. Kidney-on-a-chip: untapped opportunities

3. State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology

4. In vitro micro-physiological models for translational immunology

5. A lung/liver-on-a-chip platform for acute and chronic toxicity studies

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