A case of iatrogenic Cushing syndrome and subsequent adrenal insufficiency from a hidden ingredient in the supplement Artri Ajo King

Author:

Boncompagni Ana Carolina1,Ruiz Erin2,Rider Ashley C.2

Affiliation:

1. School of Medicine Stanford University Palo Alto California USA

2. Department of Emergency Medicine Stanford University Palo Alto California USA

Abstract

AbstractDietary supplement use is common in the United States. Supplements are regulated by the US Food and Drug Administration (FDA) under a separate set of guidelines from typical food and drug products. This case report describes a patient who presented to the emergency department (ED) with abdominal pain, vomiting, and generalized weakness. On detailed history, we learned that he had been taking a supplement called Artri Ajo King for 18 months, followed by recent abrupt cessation before his ED presentation. He was subsequently found to have a low serum cortisol level and was diagnosed with secondary adrenal insufficiency by a cosyntropin stimulation test. Ultimately, he was started on hydrocortisone with resolution of his symptoms. This case illustrates the consequence of allowing dietary supplements to be sold before FDA evaluation as well as the importance of physicians eliciting history of supplement use and offering a culturally competent discussion with their patients regarding supplement use.

Publisher

Wiley

Subject

Emergency Medicine

Reference13 articles.

1. Dietary Supplements Pose Real Dangers to Patients

2. National Institutes of Health Office of Dietary Supplements. Dietary Supplement Health and Education Act of 1994 Public Law 103–417 103rd Congress. Approved October 25 1994. Accessed May 15 2023.https://ods.od.nih.gov/About/DSHEA_Wording.aspx

3. Food and Drug Administration.Public notification: Artri King contains hidden drug ingredients April 20 2022. Accessed May 15 2023.https://www.fda.gov/drugs/medication‐health‐fraud/public‐notification‐artri‐king‐contains‐hidden‐drug‐ingredients

4. Food and Drug Administration FDA warns consumers not to purchase or use Artri and Ortiga products which may contain hidden drug ingredients. October 28 2022. Accessed May 15 2023.https://www.fda.gov/drugs/drug‐safety‐and‐availability/fda‐warns‐consumers‐not‐purchase‐or‐use‐artri‐and‐ortiga‐products‐which‐may‐contain‐hidden‐drug

5. Cushing's syndrome: from physiological principles to diagnosis and clinical care

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3