Research on promoting the asymmetric reaction of phenylacetylene with aldehydes by chloramphenicol base ligands-Reference-Cited by-同舟云学术

Research on promoting the asymmetric reaction of phenylacetylene with aldehydes by chloramphenicol base ligands

Published:2023-11-16 Issue:2 Volume:36 Page:
ISSN:0899-0042
Container-title:Chirality
language:en
Short-container-title:Chirality

Author:

Lu Baozhao¹,Zhang Ruifeng¹,Chen Congdi²,Jin Liming³,Xu Jiaqi¹,Yang Hongjun¹^ORCID

Affiliation:

1. Key Laboratory of General Chemistry of the National Ethnic Affairs Commission, School of Chemistry and Environment Southwest Minzu University Chengdu China

2. Sichuan Provincial Key Laboratory for Structural Optimization and Application of Functional Molecules Chengdu Normal University Chengdu China

3. Key Laboratory of Biotechnology and Bioresources Utilization, Ministry of Education Dalian Minzu University Dalian China

Abstract

AbstractA series of chiral ligands were synthesized using chloramphenicol base as starting materials. These ligands were applied to the asymmetric catalytic reactions of terminal alkynes with aldehydes to obtain a propargyl alcohol product in high yield (80–94%) with excellent enantioselectivities (82–96%).

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/chir.23631

Reference35 articles.

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3. 3-Aminoquinazolinones as chiral ligands in catalytic enantioselective diethylzinc and phenylacetylene addition to aldehydes

4. Investigation of catalytic activity and catalytic mechanism of chiral amino diol tridentate ligands in the asymmetric addition of aldehydes in the present of methyllithium reagent

5. Enantioselective Alkyne Addition to Aliphatic, Aromatic, and Vinyl Aldehydes Using Zn, iPrI, H8BINOL, and Ti(OiPr)4