Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection withToxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control-Reference-Cited by-同舟云学术

Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection withToxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control

Published:2004-09-15 Issue:11 Volume:34 Page:3197-3207
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Vossenkämper Anna,Struck Daniela,Alvarado-Esquivel Cosme,Went Tobias,Takeda Kioyshi,Akira Shizuo,Pfeffer Klaus,Alber Gottfried,Lochner Matthias,Förster Irmgard,Liesenfeld Oliver

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference47 articles.

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2. TNF-alpha, nitric oxide and IFN-gamma are all critical for development of necrosis in the small intestine and early mortality in genetically susceptible mice infected perorally with Toxoplasma gondii.;Liesenfeld;Parasite Immunol.,1999

3. IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii.;Suzuki;J. Immunol.,2000

4. Lamina propria CD4+ T lymphocytes synergize with murine intestinal epithelial cells to enhance proinflammatory response against an intracellular pathogen.;Mennechet;J. Immunol.,2002

5. A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice.;Khan;Proc. Natl. Acad. Sci. USA,1997

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