Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells

Author:

Kim Jung-Hyun1,Kurtz Andreas2,Yuan Bao-Zhu3,Zeng Fanyi4,Lomax Geoff5,Loring Jeanne F.6,Crook Jeremy789,Ju Ji Hyeon10,Clarke Laura11,Inamdar Maneesha S.12,Pera Martin13,Firpo Meri T.14,Sheldon Michael15,Rahman Nafees16,O’Shea Orla17,Pranke Patricia18,Zhou Qi19,Isasi Rosario20,Rungsiwiwut Ruttachuk21,Kawamata Shin22,Oh Steve23,Ludwig Tenneille24,Masui Tohru25,Novak Thomas J.26,Takahashi Tsuneo27,Fujibuchi Wataru28,Koo Soo Kyung1,Stacey Glyn N.17

Affiliation:

1. a Korea Stem Cell Bank, Center for Biomedical Sciences, Korea National Institute of Health (KNIH), Osong, South Korea

2. b Charité Universitätsmedizin Berlin, Berlin, Germany

3. c Cell Collection and Research Center, National Institutes for Food and Drug Control, Beijing, China

4. d Shanghai Institute of Medical Genetics, Shanghai Jiao Tong University, Shanghai, China

5. e California Institute for Regenerative Medicine, Oakland, CA, USA

6. f Department of Molecular Medicine Center for Regenerative Medicine The Scripps Research Institute, San Diego, CA, USA

7. g ARC Centre of Excellence for Electromaterials Science, Intelligent Polymer Research Institute, AIIM Facility, University of Wollongong, Fairy Meadow, New South Wales, Australia

8. h Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, New South Wales, Australia

9. i Department of Surgery, St. Vincent's Hospital, The University of Melbourne, Fitzroy, Victoria, Australia

10. j Catholic University, Seoul, Korea

11. k European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK

12. l Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India

13. m Jackson Laboratories, Bar Harbor, ME, USA

14. n Stem Cell Institute and Department of Medicine, University of Minnesota, Minneapolis, MN, USA

15. o Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ

16. p University of Toronto, Toronto, Ontario, Canada

17. q UK Stem Cell Bank, Division of Advanced Therapies, NIBSC, South Mimms, UK

18. r Stem Cell Research Institute, Federal University of Rio Grande do Sul, Porto Alegre, Brazil

19. s Institute of Zoology, Chinese Academy of Sciences, Beijing, China

20. t Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA

21. u Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

22. v Foundation for Biomedical Research and Innovation, Kobe, Japan

23. w Stem Cell Group, Bioprocessing Technology Institute, A*STAR, Singapore

24. x WiCell Research Institute, Madison, WI, USA

25. y Keio University/SKIP, Yokahama, Japan

26. z Cellular Dynamics International, Madison, WI, USA

27. aa University of Kyoto, Kyoto, Japan

28. bb Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

Abstract

Abstract This article summarizes the recent activity of the International Stem Cell Banking Initiative (ISCBI) held at the California Institute for Regenerative Medicine (CIRM) in California (June 26, 2016) and the Korean National Institutes for Health in Korea (October 19–20, 2016). Through the workshops, ISCBI is endeavoring to support a new paradigm for human medicine using pluripotent stem cells (hPSC) for cell therapies. Priority considerations for ISCBI include ensuring the safety and efficacy of a final cell therapy product and quality assured source materials, such as stem cells and primary donor cells. To these ends, ISCBI aims to promote global harmonization on quality and safety control of stem cells for research and the development of starting materials for cell therapies, with regular workshops involving hPSC banking centers, biologists, and regulatory bodies. Here, we provide a brief overview of two such recent activities, with summaries of key issues raised.

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Developmental Biology,General Medicine

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