Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset

Author:

Cabrera Susanne M.1,Wang Xujing2,Chen Yi-Guang1,Jia Shuang1,Kaldunski Mary L.1,Greenbaum Carla J.3,Mandrup-Poulsen Thomas45,Hessner Martin J.1, ,

Affiliation:

1. The Max McGee National Research Center for Juvenile Diabetes; Children's Research Institute of Children's Hospital of Wisconsin; and Department of Pediatrics at the Medical College of Wisconsin; Milwaukee WI USA

2. Systems Biology Center; the National Heart; Lung; and Blood Institute, the National Institutes of Health; Bethesda MD USA

3. Diabetes Research Program; Benaroya Research Institute; Seattle WA USA

4. Department of Biomedical Sciences; Faculty of Health and Medical Sciences; University of Copenhagen; Copenhagen Denmark

5. Department of Molecular Medicine and Surgery; Karolinska Institutet; Stockholm Sweden

Funder

Juvenile Diabetes Research Foundation International

American Diabetes Association

National Institutes of Health

National Center for Advancing Translational Sciences, National Institutes of Health

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

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