Aging affects B-cell antigen receptor repertoire diversity in primary and secondary lymphoid tissues

Author:

Tabibian-Keissar Hilla12,Hazanov Lena1,Schiby Ginette23,Rosenthal Noemie1,Rakovsky Aviya1,Michaeli Miri1,Shahaf Gitit Lavy1,Pickman Yishai1,Rosenblatt Kinneret2,Melamed Doron4,Dunn-Walters Deborah5,Mehr Ramit1,Barshack Iris23

Affiliation:

1. The Mina and Everard Goodman Faculty of Life Sciences; Bar-Ilan University; Ramat Gan Israel

2. Department of Pathology; Sheba Medical Center; Ramat Gan Israel

3. Sackler School of Medicine; Tel Aviv University; Tel Aviv Israel

4. Department of Immunology; Technion Faculty of Medicine; Haifa Israel

5. Division of Immunology, Infection, and Inflammatory Diseases; King's College London; Faculty of Life Sciences & Medicine; London United Kingdom

Funder

Israel Science Foundation

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference47 articles.

1. B cell repertoire and ageing;Dunn-Walters;Curr. Opin. Immunol,2010

2. B-cell diversity decreases in old age and is correlated with poor health status;Gibson;Aging Cell,2009

3. B-cell responses to vaccination at the extremes of age;C.-A.;Nat. Rev. Immunol.,2009

4. Mechanisms of immunosenescence;Caruso;Immun. Ageing I A.,2009

5. B cell maintenance and function in aging;Kogut;Semin. Immunol.,2012

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