Characterization of a conditional interleukin-1 receptor 1 mouse mutant using the Cre/LoxP system

Author:

Abdulaal Wesam H.12,Walker Catherine R.1,Costello Ryan1,Redondo-Castro Elena1,Mufazalov Ilgiz A.3,Papaemmanouil Athina1,Rothwell Nancy J.1,Allan Stuart M.1,Waisman Ari3,Pinteaux Emmanuel1,Müller Werner1

Affiliation:

1. Faculty of Life Sciences; University of Manchester; Manchester UK

2. Biochemistry Department, Faculty of Sciences; King Abdulaziz University; Jeddah Kingdom of Saudi Arabia

3. Institute for Molecular Medicine; Medical University of Johannes Gutenberg-University of Mainz; Mainz Germany

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference14 articles.

1. Phenotypic and functional characterization of mice that lack the type I receptor for IL-1;Glaccum;J. Immunol.,1997

2. Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice;Labow;J. Immunol.,1997

3. IL-1-dependent, IL-1R1-independent resistance to gastrointestinal nematodes;Humphreys;Eur. J. Immunol.,2009

4. Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type I receptor;Touzani;J. Neurosci.,2002

5. Interleukin-1R3 mediates interleukin-1-induced potassium current increase through fast activation of Akt kinase;Qian;Proc. Natl. Acad. Sci. USA,2012

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