Death and liver transplantation within 2 years of onset of drug-induced liver injury

Author:

Hayashi Paul H.1,Rockey Don C.2,Fontana Robert J.3,Tillmann Hans L.4,Kaplowitz Neil5,Barnhart Huiman X.6,Gu Jiezhan6,Chalasani Naga P.7,Reddy K. Rajender8,Sherker Averell H.9,Hoofnagle Jay H.9,

Affiliation:

1. Division of Gastroenterology and Hepatology; University of North Carolina; Chapel Hill NC

2. Division of Gastroenterology; Medical University of South Carolina; Charleston SC

3. Division of Gastroenterology; University of Michigan; Ann Arbor MI

4. Division of Gastroenterology, East Carolina University; Greenville NC

5. Division of Gastroenterology; University of Southern California; Los Angeles CA

6. Duke Clinical Research Institute; Duke University; Durham NC

7. Division of Gastroenterology; Indiana University School of Medicine; Indianapolis IN

8. Division of Gastroenterology; University of Pennsylvania; Philadelphia PA

9. Liver Disease Research Branch; Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health; Bethesda MD

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Clinical and Translational Science Award

National Cancer Institute

NIH

Publisher

Wiley

Subject

Hepatology

Reference22 articles.

1. Drug-induced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10-year period;Andrade;Gastroenterology,2005

2. Features and outcomes of 899 patients with drug-induced liver injury: the DILIN prospective study;Chalasani;Gastroenterology,2015

3. Outcome and prognostic markers in severe drug-induced liver disease;Bjornsson;Hepatology,2005

4. Subject race and liver biochemical profile are strongly assoicated with clinical outcomes and chronic liver injury: Results from the DILIN prospective study;Fontana;Hepatology,2012

5. Idiosyncratic drug-induced liver injury is associated with substantial morbidity and mortality within 6 months from onset;Fontana;Gastroenterology,2014

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