Folic acid supplementation use and the MTHFR C677T polymorphism in orofacial clefts etiology: An individual participant data pooled-analysis

Author:

Butali Azeez1,Little Julian2,Chevrier Cécile3,Cordier Sylvian3,Steegers-Theunissen Regine,Jugessur Astanand,Oladugba Bola4,Mossey Peter A.5

Affiliation:

1. Department of Pediatrics; University of Iowa; Iowa

2. Department of Epidemiology and Community Medicine; University of Ottawa; Canada

3. Institut National de la Santé et de Recherche Médicale; Rennes; France

4. Department of Biostatistics; University of Nigeria; Nsukka; Nigeria

5. Dundee Dental School and Hospital; University of Dundee; UK

Publisher

Wiley

Subject

Developmental Biology,Embryology,General Medicine,Pediatrics, Perinatology and Child Health

Reference30 articles.

1. Evidence for gene-environment interaction in a genome wide study of nonsyndromic cleft palate;Beaty;Genet Epidemiol.,2011

2. Folate and one-carbon metabolism gene polymorphisms and their associations with oral facial clefts;Boyles;Am J Med Genet A,2008

3. Fetal and maternal MTHFR C677T genotype, maternal folate intake and the risk of nonsyndromic oral clefts;Chevrier;Am J Med Genet A,2007

4. Effects and safety of periconceptional folate supplementation for preventing birth defects;De-Regil;Cochrane Database Syst Rev,2010

5. Cleft lip and palate: understanding genetic and environmental influences;Dixon;Nat Rev Genet,2011

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