Ginkgetin Blocks Constitutive STAT3 Activation and Induces Apoptosis through Induction of SHP-1 and PTEN Tyrosine Phosphatases

Author:

Baek Seung Ho1,Lee Jae Hwi1,Ko Jeong-Hyeon1,Lee Hanwool1,Nam Dongwoo1,Lee Seok Geun1,Yang Woong Mo1,Um Jae-Young1,Lee Junhee1,Kim Sung-Hoon1,Shim Bum Sang1,Ahn Kwang Seok1

Affiliation:

1. College of Korean Medicine; Kyung Hee University; 24 Kyungheedae-ro, Dongdaemun-gu Seoul 130-701 Republic of Korea

Funder

Korea government

Korean Ministry of Education, Science and Technology

Publisher

Wiley

Subject

Pharmacology

Reference38 articles.

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2. Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?;Aggarwal;Ann N Y Acad Sci,2009

3. Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease;Ahlemeyer;Pharmacopsychiatry,2003

4. Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1;Ahn;Cancer Res,2008

5. Bcl-2 and Bcl-xL in peroxide-resistant A549 and U87MG cells;Bojes;Toxicol Sci,1998

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