Dietary strategies in non‐alcoholic fatty liver disease patients: From evidence to daily clinical practice, a systematic review

Author:

Hadefi Alia12ORCID,Arvanitakis Marianna1ORCID,Trépo Eric12,Zelber‐Sagi Shira34

Affiliation:

1. Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology CUB Hôpital Erasme Université Libre de Bruxelles Hôpital Universitaire de Bruxelles (HUB) Brussels Belgium

2. Laboratory of Experimental Gastroenterology Université Libre de Bruxelles Brussels Belgium

3. Faculty of Social Welfare and Health Sciences School of Public Health University of Haifa Haifa Israel

4. Department of Gastroenterology Tel‐Aviv Medical Centre Tel‐Aviv Israel

Abstract

AbstractLifestyle modification comprising calorie restriction (CR) and increased physical activity enabling weight loss is the first‐line of treatment for non‐alcoholic fatty liver disease (NAFLD). However, CR alone is not optimal and evidence suggests that dietary pattern and composition are also critical in NAFLD management. Accordingly, high consumption of red and processed meat, saturated fat, added sugar, and sweetened beverages are associated with an increased risk of developing NAFLD and hepatocellular carcinoma, while other foods and compounds such as fish, olive oil, and polyphenols are, in contrast, beneficial for metabolic disorders. Therefore, several dietary interventions have been studied in order to determine which strategy would be the most beneficial for NAFLD. The evidence regarding the effectiveness of different dietary interventions such as low carbohydrate/low‐fat diet, time‐restricted eating diet, CR, and the well‐studied Mediterranean diet is summarized.

Publisher

Wiley

Subject

Gastroenterology,Oncology

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