Exploring the limits of the usefulness of mutagenesis in studies of allosteric mechanisms
Author:
Affiliation:
1. Department of Biochemistry and Molecular BiologyThe University of Kansas Medical Center Kansas City Kansas
2. Department of BiologyUniversity of Waterloo Waterloo Ontario Canada
Funder
National Institutes of Health
Publisher
Wiley
Subject
Genetics (clinical),Genetics
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/humu.23239
Reference44 articles.
1. Effector Analogues Detect Varied Allosteric Roles for Conserved Protein−Effector Interactions in Pyruvate Kinase Isozymes
2. What Mutagenesis Can and Cannot Reveal About Allostery
3. Effects of Conserved Residues on the Regulation of Rabbit Muscle Pyruvate Kinase
4. Synergistic effects of proton and phenylalanine on the regulation of muscle pyruvate kinase
5. Energetics of allosteric regulation in muscle pyruvate kinase
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