T‐495, a novel low cooperative M1receptor positive allosteric modulator, improves memory deficits associated with cholinergic dysfunction and is characterized by low gastrointestinal side effect risk-Reference-Cited by-同舟云学术

T‐495, a novel low cooperative M1receptor positive allosteric modulator, improves memory deficits associated with cholinergic dysfunction and is characterized by low gastrointestinal side effect risk

Published:2020-01-28 Issue:1 Volume:8 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

Mandai Takao¹,Sako Yuu¹,Kurimoto Emi¹,Shimizu Yuji¹²,Nakamura Minoru¹,Fushimi Makoto¹,Maeda Ryouta¹,Miyamoto Maki³,Kimura Haruhide¹^ORCID

Affiliation:

1. Neuroscience Drug Discovery Unit Research Takeda Pharmaceutical Company Limited Fujisawa Japan

2. Biomolecular Research Laboratories Research Takeda Pharmaceutical Company Limited Fujisawa Japan

3. Drug Metabolism and Pharmacokinetics Research Laboratories Research Takeda Pharmaceutical Company Limited Fujisawa Japan

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.560

Reference61 articles.

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2. Acetylcholine: a neurotransmitter for learning and memory?

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5. Delusions associated with elevated muscarinic binding in dementia with Lewy bodies

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