Stereoselective Determination of Metoprolol and its Metabolite α-Hydroxymetoprolol in Plasma by LC-MS/MS: Application to Pharmacokinetics during Pregnancy-Reference-Cited by-同舟云学术

Stereoselective Determination of Metoprolol and its Metabolite α-Hydroxymetoprolol in Plasma by LC-MS/MS: Application to Pharmacokinetics during Pregnancy

Published:2012-10-24 Issue:1 Volume:25 Page:1-7
ISSN:0899-0042
Container-title:Chirality
language:en
Short-container-title:Chirality

Author:

Antunes Natalícia De Jesus¹,Cavalli Ricardo Carvalho²,Marques Maria Paula¹,Lanchote Vera Lucia¹

Affiliation:

1. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto; Universidade de São Paulo; Ribeirão Preto; São Paulo; Brazil

2. Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina de Ribeirão Preto; Universidade de São Paulo; Ribeirão Preto; São Paulo; Brazil

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry

Reference17 articles.

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2. Disposition of the adrenergic blocker metoprolol and its metabolite OH-metoprolol maternal plasma, amniotic fluid and capillary blood of the neonate;Lindeberg;Acta Obstet Gynecol Scand Suppl,1984

3. Radioceptor assay of metoprolol in human plasma: comparison with an enantiospecific high-performance liquid chromatographic (HPLC) procedure;Spahn;Pharm Res,1989

4. Determination of the enantiomers of metoprolol and its major acidic metabolite in human urine by high-performance liquid chromatography with fluorescence detection;Li;J Chromatogr B,1995

5. The β1 and β2-adrenoceptor affinity and β1-blocking potency of S- and R-metoprolol;Wahlund;Br J Pharmacol,1990

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