<scp>DNA</scp> ‐Thioguanine Nucleotides as a Marker for Thiopurine Induced Late Leukopenia after Dose Optimizing by <scp> <i>NUDT15</i> C415T </scp> in Chinese Patients with <scp>IBD</scp>-Reference-Cited by-同舟云学术

DNA ‐Thioguanine Nucleotides as a Marker for Thiopurine Induced Late Leukopenia after Dose Optimizing by NUDT15 C415T in Chinese Patients with IBD

Published:2022-09-11 Issue:6 Volume:112 Page:1236-1242
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin Pharma and Therapeutics

Author:

Zhu Xia¹²³,Chao Kang¹³,Yang Ting²,Wang Xue‐ding²,Guan Shaoxing²,Tang Jian¹³,Xie Wen⁴,Yu Ai‐ming⁵,Yang Qing fan¹³,Li Miao¹³,Yang Hong‐sheng¹³,Diao Na¹³,Hu Pin‐jin¹³,Gao Xiang¹³^ORCID,Huang Min²

Affiliation:

1. Department of Gastroenterology, The Sixth Affiliated Hospital Sun Yat‐sen University Guangzhou China

2. Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences Sun Yat‐sen University Guangzhou China

3. Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Supported by National Key Clinical Discipline Guangzhou China

4. Center for Pharmacogenetics and Department of Pharmaceutical Sciences University of Pittsburgh Pittsburgh Pennsylvania USA

5. Department of Biochemistry and Molecular Medicine UC Davis School of Medicine Sacramento California USA

Funder

China Postdoctoral Science Foundation

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2730

Reference37 articles.

1. Thiopurines in Inflammatory Bowel Disease: New Findings and Perspectives

2. Thiopurine therapy in inflammatory bowel disease patients: Analyses of two 8-year intercept cohorts

3. Review article: recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease

4. Timing of Myelosuppression During Thiopurine Therapy for Inflammatory Bowel Disease: Implications for Monitoring Recommendations

5. Revisiting the Role of Thiopurines in Inflammatory Bowel Disease Through Pharmacogenomics and Use of Novel Methods for Therapeutic Drug Monitoring

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1. Reply to: Therapeutic Drug Monitoring for IBD Children on Thioguanine;Journal of Pediatric Gastroenterology & Nutrition;2023-06-22