Non‐negative matrix factorisation of Raman spectra finds common patterns relating to neuromuscular disease across differing equipment configurations, preclinical models and human tissue

Author:

Alix James J. P.12ORCID,Plesia Maria1,Schooling Chlöe N.13,Dudgeon Alexander P.456,Kendall Catherine A.4,Kadirkamanathan Visakan3,McDermott Christopher J.12,Gorman Gráinne S.78,Taylor Robert W.78,Mead Richard J.12,Shaw Pamela J.12,Day John C.6

Affiliation:

1. Sheffield Institute for Translational Neuroscience University of Sheffield Sheffield UK

2. Neuroscience Institute University of Sheffield Sheffield UK

3. Department of Automatic Control and Systems Engineering University of Sheffield Sheffield UK

4. Biophotonics Research Unit Gloucestershire Hospitals NHS Foundation Trust Gloucester UK

5. Biomedical Spectroscopy, School of Physics and Astronomy University of Exeter Exeter UK

6. Interface Analysis Centre, School of Physics University of Bristol Bristol UK

7. Wellcome Centre for Mitochondrial Research, Translational and Clinical Research Institute, Faculty of Medical Sciences Newcastle University Newcastle upon Tyne UK

8. NHS Highly Specialised Service for Rare Mitochondrial Disorders Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle upon Tyne UK

Funder

Academy of Medical Sciences

Medical Research Council

National Institute for Health and Care Research

NIHR Sheffield Biomedical Research Centre

NIHR Sheffield Clinical Research Facility

Engineering and Physical Sciences Research Council

Wellcome Trust Centre for Mitochondrial Research

Lily Foundation

NIHR Newcastle Biomedical Research Centre

Pathological Society of Great Britain and Ireland

University of Sheffield

Alzheimer Society

NIHR Oxford Biomedical Research Centre

Publisher

Wiley

Subject

Spectroscopy,General Materials Science

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