Affiliation:
1. Key Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, Institute of Optoelectronic Materials and Devices Collage of Optical and Electronic Technology China Jiliang University 310018 Hangzhou People's Republic of China
Abstract
AbstractDesign and synthesis of drug delivery carrier for targeted and controlled drug release is very vital but challenging. In this work, based on organic ligand molecule 2,4,6‐tris(4‐carboxyphenyl)aniline (BTB‐NH2), a porous hydrogen‐bonded organic framework material HOF‐BTB‐NH2 was designed and synthesized for targeted drug delivery. The anti‐inflammatory drug Ibuprofen (IBU) was effectively loaded in the HOF‐BTB‐NH2, and it took 6 hours to release IBU completely in PBS buffer solution. This work demonstrates that the porous HOF materials are promising candidates for targeted drug delivery applications.
Funder
Natural Science Foundation of Zhejiang Province
Cited by
3 articles.
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