Rapid LC-MS/MS method for quantification of vinorelbine and 4-O- deacetylvinorelbine in human whole blood suitable to monitoring oral metronomic anticancer therapy-Reference-Cited by-同舟云学术

Rapid LC-MS/MS method for quantification of vinorelbine and 4-O- deacetylvinorelbine in human whole blood suitable to monitoring oral metronomic anticancer therapy

Published:2018-05-29 Issue:9 Volume:32 Page:e4282
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Corona Giuseppe¹^ORCID,Gusella Milena²,Gaspardo Anna³,Miolo Gianmaria⁴,Bertolaso Laura²,Pezzolo Elisa²,Pasini Felice⁵,Steffan Agostino¹,Caruso Donatella³

Affiliation:

1. Immunopathology and Cancer Biomarkers Unit, Translational Research Department; IRCCS National Cancer Institute; Aviano Italy

2. Oncology Department; Santa Maria della Misericordia Hospital; Rovigo Italy

3. Pharmacological and Biomolecular Science Department; University of Milan Milan; Italy

4. Medical and Preventive Oncology Unit; IRCCS National Cancer Institute; Aviano Italy

5. Medical Oncology Unit; Piero Pederzoli Hospital; Peschiera del Garda Italy

Funder

Lega Italiana per la lotta contro i tumori, sezione di Rovigo.

Specialized Research Fund for the Doctoral Program of the Higher Education University of Milan

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bmc.4282/fullpdf

Reference27 articles.

1. Pharmacokinetics of metronomic chemotherapy: A neglected but crucial aspect;Bocci;Nature Reviews Clinical Oncology,2016

2. Evaluation of oral versus intravenous dose of vinorelbine to achieve equivalent blood exposures in patients with solid tumours;Bourgeois;Cancer Chemotherapy and Pharmacology,2007

3. Dose selection trial of metronomic oral vinorelbine monotherapy in patients with metastatic cancer: A hellenic cooperative oncology group clinical translational study;Briasoulis;BMC Cancer,2013

4. Dose-ranging study of metronomic oral vinorelbine in patients with advanced refractory cancer;Briasoulis;Clinical Cancer Research,2009

5. The effects of food on the pharmacokinetic profile of oral vinorelbine;Bugat;Cancer Chemotherapy and Pharmacology,2002

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2. Oral Metronomic Vinorelbine (OMV) in elderly or pretreated patients with advanced non small cell lung cancer: outcome and pharmacokinetics in the real world;Investigational New Drugs;2018-06-28