UV–vis Study on β‐Cyclodextrin as Dual Function for Synthesis AgNPs and Antibacterial Application

Author:

Nurkhaliza Farrah12,Fathoni Ahmad2,Yati Indri1,Prastya Muhammad Eka3,Jenie S. N. Aisyiyah14,Andreani Agustina Sus14ORCID

Affiliation:

1. Research Centre for Chemistry National Research and Innovation Agency (BRIN) Kawasan Puspiptek, Building 452, Serpong Tangerang Selatan Banten 15314 Indonesia

2. Chemistry Department Syarif Hidayatullah State Islamic University Jln. Ir. H. Djuanda No. 95, Ciputat Tangerang Selatan Banten 15412 Indonesia

3. Research Centre for Pharmaceutical Ingredients and Traditional Medicine National Research and Innovation Agency (BRIN) Kawasan Puspiptek Serpong Tangerang Selatan Banten 15314 Indonesia

4. BRIN and ITB Collaboration Research Centre for Biosensor and Biodevices Jln. Ganesha 10 Bandung Jawa Barat 40132 Indonesia

Abstract

AbstractThe current study reveals the synthesis of silver nanoparticles (AgNPs) with β‐cyclodextrin (β‐CDs) as a dual function, reducing, and stabilizing agent. UV–vis study is carried out to monitor the optimum condition of AgNPs formation. It is observed that setting pH at 12, 1:33 concentration ratio of AgNO3 to β‐CDs, and 5 min of incubation time are the optimum condition to synthesize AgNPs. The stability of AgNPs 4 weeks after synthesized is confirmed by the UV–vis spectra. Fourier transform infrared (FTIR) characterization reveals there is a peak appearing assigned to C=O which proves a redox reaction occurs between AgNO3 and β‐CDs. Gram‐positive (Bacillus subtilis and Staphylococcus aureus) and Gram‐negative bacteria (Escherichia coli and Pseudomonas aeruginosa) are tested to investigate the antibacterial activity of AgNPs. This study shows that AgNPs exhibit inhibition of bacterial growth.

Publisher

Wiley

Subject

Materials Chemistry,Polymers and Plastics,Organic Chemistry,Condensed Matter Physics

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