Restrictive vs liberal red blood cell transfusion strategies in patients with acute myocardial infarction and anemia: Rationale and design of the REALITY trial

Author:

Ducrocq Gregory1ORCID,Calvo Gonzalo2,González‐Juanatey José Ramón3,Durand‐Zaleski Isabelle4,Avendano‐Sola Cristina5,Puymirat Etienne6ORCID,Lemesle Gilles7ORCID,Arnaiz Joan Albert8,Martínez‐Sellés Manuel9ORCID,Rousseau Alexandra10,Cachanado Marine10,Vicaut Eric11,Silvain Johanne12,Karam Carma13,Danchin Nicolas6,Simon Tabassome14,Steg Philippe Gabriel115ORCID,

Affiliation:

1. Université de Paris, AP‐HP French Alliance for Cardiovascular Trials (FACT), INSERM U1148 Paris France

2. Àrea del Medicament Hospital Clínic of Barcelona University of Barcelona Barcelona Spain

3. Cardiology Department, University Hospital, IDIS, CIBERCV University of Santiago de Compostela Santiago de Compostela Spain

4. AP‐HP Health Economics Research Unit Hotel Dieu Hospital, INSERM UMR 1153 CRESS Paris France

5. Clinical Pharmacology Service Hospital Universitario Puerta de Hierro‐Majadahonda Madrid Spain

6. Hôpital Européen Georges Pompidou, AP‐HP French Alliance for Cardiovascular Trials (FACT), and Université de Paris Paris France

7. Institut Cœur Poumon, Centre Hospitalier Universitaire de Lille, Faculté de Médecine de Lille Université de Lille, Institut Pasteur de Lille, Inserm U1011, F‐59000 Lille, France; French Alliance for Cardiovascular Trials (FACT) Paris France

8. Clinical Trials Unit, Clinical Pharmacology Department Hospital Clinic Barcelona Spain

9. Servicio de Cardiología, Hospital Universitario Gregorio Marañón, CIBERCV; Universidad Europea Universidad Complutense Madrid Spain

10. Clinical Research Platform (URCEST‐CRB‐CRCEST), AP‐HP Hôpital Saint Antoine Paris France

11. AP‐HP, Department of Biostatistics Université Paris‐Diderot, Sorbonne‐Paris Cité, Fernand Widal Hospital France

12. Sorbonne Université, ACTION Study Group Institut de Cardiologie, Hôpital Pitié‐Salpêtrière, AP‐HP, INSERM UMRS 1166 Paris France

13. Cardiology Department, Ambroise Paré Hospital, AP‐HP, Boulogne University of Versailles‐Saint Quentin en Yvelines Boulogne‐Billancourt France

14. Department of Clinical Pharmacology‐Clinical Research Platform (URCEST‐CRB‐CRCEST), AP‐HP, Hôpital Saint Antoine, French Alliance for Cardiovascular Trials (FACT) Sorbonne‐Université Paris France

15. Royal Brompton Hospital Imperial College London UK

Funder

Instituto de Salud Carlos III

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine,General Medicine

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