Lysine 268 adjacent to transmembrane helix 5 of hamster P‐glycoprotein is the major photobinding site of iodomycin in CHO B30 cells-Reference-Cited by-同舟云学术

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Lysine 268 adjacent to transmembrane helix 5 of hamster P‐glycoprotein is the major photobinding site of iodomycin in CHO B30 cells

Published:2021-02-28 Issue:4 Volume:11 Page:1084-1092
ISSN:2211-5463
Container-title:FEBS Open Bio
language:en
Short-container-title:FEBS Open Bio

Author:

Demmer Annette¹,Thole Hubert¹,Raida Manfred²,Tümmler Burkhard¹³^ORCID

Affiliation:

1. Klinische Forschergruppe Klinik für Pädiatrische Pneumologie Allergologie und Neonatologie Medizinische Hochschule Hannover Germany

2. Singapore Lipidomics Incubator (SLING) Life Sciences Institute National University of Singapore Singapore

3. Biomedical Research in Endstage and Obstructive Lung Disease Hannover Deutsches Zentrum für Lungenforschung (DZL) Medizinische Hochschule Hannover Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/2211-5463.13112

Reference33 articles.

1. The molecular basis of multidrug resistance in cancer: The early years of P-glycoprotein research

2. P-glycoprotein ABCB1: a major player in drug handling by mammals

3. Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

4. Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

5. Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1

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