Characterization of epidermal growth factor receptor ( EGFR ) P848L, an unusual EGFR variant present in lung cancer patients, in a murine Ba/F3 model-Reference-Cited by-同舟云学术

Characterization of epidermal growth factor receptor ( EGFR ) P848L, an unusual EGFR variant present in lung cancer patients, in a murine Ba/F3 model

Published:2019-09-07 Issue:10 Volume:9 Page:1689-1704
ISSN:2211-5463
Container-title:FEBS Open Bio
language:en
Short-container-title:FEBS Open Bio

Author:

Sarcar Bhaswati¹,Gimbrone Nicholas T.¹,Wright Gabriela¹,Remsing Rix Lily L.²,Gordian Edna R.³,Rix Uwe²,Chiappori Alberto A.³⁴,Reuther Gary W.¹,Santiago‐Cardona Pedro G.⁵,Muñoz‐Antonia Teresita³,Cress William Douglas¹⁴^ORCID

Affiliation:

1. Department of Molecular Oncology H. Lee Moffitt Cancer Center and Research Institute Tampa FL USA

2. Department of Drug Discovery H. Lee Moffitt Cancer Center and Research Institute Tampa FL USA

3. Department of Tumor Biology H. Lee Moffitt Cancer Center and Research Institute Tampa FL USA

4. Department of Thoracic Oncology H. Lee Moffitt Cancer Center and Research Institute Tampa FL USA

5. Biochemistry and Cancer Biology Divisions Ponce Health Sciences University Puerto Rico

Funder

National Institutes of Health

Florida Department of Health

National Cancer Institute

Publisher

Wiley

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/2211-5463.12702

Reference61 articles.

1. Epidermal growth factor receptor mutations in lung cancer

2. EGFR exon 20 insertion mutations in non-small-cell lung cancer: preclinical data and clinical implications

3. Structural, Biochemical, and Clinical Characterization of Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations in Lung Cancer

4. Effectiveness of Gefitinib against Non–Small-Cell Lung Cancer with the Uncommon EGFR Mutations G719X and L861Q

5. Not all epidermal growth factor receptor mutations in lung cancer are created equal: Perspectives for individualized treatment strategy

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