ALDH2 Polymorphism rs671, but Not ADH1B Polymorphism rs1229984, Increases Risk for Hypo-HDL-Cholesterolemia in a/a Carriers Compared to the G/G Carriers

Author:

Imatoh Takuya12ORCID,Yengo Loic3,Rocheleau Ghislain3,Kamimura Seiichiro4,Maeda Shiro56,Miyazaki Motonobu7,Froguel Philippe38

Affiliation:

1. Department of Preventive Medicine and Public Health, Faculty of Medicine; Fukuoka University; 7-45-1, Nanakuma Jonan-ku, Fukuoka, 814-0180 Japan

2. Division of Medical Safety Science; National Institute of Health Sciences; 3-25-26, Tonomachi, Kawasaki-ku, Kanagawa, 210-0821 Japan

3. Université de Lille 2, CNRS, CHU Lille, Institut Pasteur de Lille; UMR 8199 - EGID, Pôle recherche, 1 place de Verdun, Lille, 59045 Cedex France

4. Department of Internal Medicine; Division of Preventive Medicine; Tenjin Clinic, 2-12-1, Tenjin, Chuou-ku, Fukuoka, Fukuoka, 810-0001 Japan

5. Department of Advanced Genomic and Laboratory Medicine, Graduate School of Medicine; University of the Ryukyus; 207 Banchi Uehara, Nishihara-cho, Nakagami-gun, Okinawa, 9030215 Japan

6. Division of Clinical Laboratory and Blood Transfusion; University of the Ryukyus Hospital; 207 Banchi Uehara, Nishihara-cho, Nakagami-gun, Okinawa, 9030215 Japan

7. Saitama City Institute of Health Science and Research; 7-5-12, Suzuya, Chuou-ku, Saitama, 338-0013 Japan

8. Department of Genomics of Common Disease; School of Public Health, Imperial College; South Kensington Campus, London, SW7 2AZ UK

Funder

Japan Society for the Promotion of Science

Grant-in-Aid for Young Scientists (B)

JSPS Grant-in-Aid for Exploratory Research

Publisher

Wiley

Subject

Cell Biology,Organic Chemistry,Biochemistry

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