1. Department of Cardiology; Hirosaki University Graduate School of Medicine; Hirosaki Japan
2. Department of Health Promotion; Hirosaki University Graduate School of Health Science; Hirosaki Japan
3. Department of Hypertension and Stroke Internal Medicine; Hirosaki University Graduate School of Medicine; Hirosaki Japan
4. Faculty of Discovery and Biotechnology II; Asubio Pharma Co., Ltd.; 6-4-3 Minatojima-Minamimachi Chuo-ku Kobe 650-0047 Japan