1. Department of Biostatistics; Johns Hopkins University; 615 N. Wolfe St. Baltimore MD 21205 U.S.A.
2. Department of Statistics; North Carolina State University; 2311 Stinson Drive Campus Raleigh NC 27695 U.S.A.
3. Biometrics Research; Merck & Company; RY 33-300 Rahway NJ 07065 U.S.A.
4. Department of Epidemiology; Johns Hopkins University, Bloomberg School of Public Health; Baltimore MD U.S.A.