O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radiotherapy w-Reference-Cited by-同舟云学术

O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radiotherapy w

Published:2012-02-22 Issue:18 Volume:118 Page:4545-4554
ISSN:0008-543X
Container-title:Cancer
language:en
Short-container-title:Cancer

Author:

Lechapt-Zalcman Emmanuèle,Levallet Guénaëlle,Dugué Audrey Emmanuelle,Vital Anne,Diebold Marie-Danièle,Menei Philippe,Colin Philippe,Peruzzy Philippe,Emery Evelyne,Bernaudin Myriam,Chapon Françoise,Guillamo Jean-Sébastien

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference21 articles.

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2. MGMT gene silencing and benefit from temozolomide in glioblastoma;Hegi;N Engl J Med.,2005

3. Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomas;Brell;Clin Cancer Res.,2005

4. Identification of regions correlating MGMT promoter methylation and gene expression in glioblastomas;Everhard;Neuro Oncol.,2009

5. MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951;van den Bent;J Clin Oncol.,2009

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