Free Flap Outcomes for Head and Neck Surgery in Patients with COVID‐19

Author:

Domack Aaron1,Sandelski Morgan M.1,Ali Syed2,Blackwell Keith E.3,Buchakjian Marisa4,Bur Andrés M.5ORCID,Cannady Steven B.6,Castellanos Carlos X.7,Ducic Yadranko8,Ghanem Tamer A.9,Huang Andrew T.10,Jackson Ryan S.11,Kokot Niels7,Li Shawn2,Pipkorn Patrik11,Puram Sidharth V.11,Rezaee Rod2,Rajasekaran Karthik6,Shnayder Yelizaveta5,Sinha Uttam K.7,Sukato Daniel3,Suresh Neeraj6,Tamaki Akina2,Thomas Carissa M.12ORCID,Thorpe Eric J.1,Wax Mark K.13,Yang Sara13,Ziegler Andrea1,Pittman Amy L.1

Affiliation:

1. Department of Otolaryngology Loyola University Medical Center Maywood Illinois USA

2. Department of Otolaryngology University Hospitals Cleveland Medical Center Cleveland Ohio USA

3. Department of Otolaryngology David Geffen School of Medicine at University of California Los Angeles Los Angeles California USA

4. Department of Otolaryngology University of Iowa Health Care Iowa City Iowa USA

5. Department of Otolaryngology University of Kansas Medical Center Kansas City Kansas USA

6. Department of Otolaryngology University of Pennsylvania Medicine Philadelphia Pennsylvania USA

7. Caruso Department of Otolaryngology University of Southern California Los Angeles California USA

8. Dallas/Fort Worth Head & Neck Cancer Center of Texas Texas USA

9. Department of Otolaryngology Henry Ford Health Detroit Michigan USA

10. Department of Otolaryngology Baylor College of Medicine Houston Texas USA

11. Department of Otolaryngology Washington University School of Medicine St. Louis Missouri USA

12. Department of Otolaryngology‐Head & Neck Surgery University of Alabama at Birmingham Birmingham Alabama USA

13. Department of Otolaryngology Oregon Health & Science University Portland Oregon USA

Abstract

IntroductionCoronavirus disease 2019 (COVID‐19) affects the vascular system, subjecting patients to a hypercoagulable state. This is of particular concern for the success of microvascular free flap reconstruction. This study aims to report head and neck free flap complications in patients with COVID‐19 during the perioperative period. We believe these patients are more likely to experience flap complications given the hypercoagulable state.MethodsThis is a multi‐institutional retrospective case series of patients infected with COVID‐19 during the perioperative period for head and neck free flap reconstruction from March 2020 to January 2022.ResultsData was collected on 40 patients from 14 institutions. Twenty‐one patients (52.5%) had a positive COVID‐19 test within 10 days before surgery and 7 days after surgery. The remaining patients had a positive test earlier than 10 days before surgery. A positive test caused a delay in surgery for 16 patients (40.0%) with an average delay of 44.7 days (9–198 days). Two free flap complications (5.0%) occurred with no free flap deaths. Four patients (10.0%) had surgical complications and 10 patients had medical complications (25.0%). Five patients (12.5%) suffered from postoperative COVID‐19 pneumonia. Three deaths were COVID‐19‐related and one from cancer recurrence during the study period.ConclusionDespite the heightened risk of coagulopathy in COVID‐19 patients, head and neck free flap reconstructions in patients with COVID‐19 are not at higher risk for free flap complications. However, these patients are at increased risk of medical complications.Level of Evidence4 Laryngoscope, 2023

Publisher

Wiley

Subject

Otorhinolaryngology

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