Design, synthesis, and in vitro biological evaluation of novel thiazolopyrimidine derivatives as antileishmanial compounds

Author:

Istanbullu Huseyin1ORCID,Bayraktar Gulsah2ORCID,Akbaba Hasan3ORCID,Cavus Ibrahim4,Coban Gunes2ORCID,Debelec Butuner Bilge3ORCID,Kilimcioglu Ali Ahmet4,Ozbilgin Ahmet4ORCID,Alptuzun Vildan2ORCID,Erciyas Ercin2

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of PharmacyIzmir Katip Celebi University Cigli Izmir Turkey

2. Department of Pharmaceutical Chemistry, Faculty of PharmacyEge University Bornova Izmir Turkey

3. Department of Pharmaceutical Biotechnology, Faculty of PharmacyEge University Bornova Izmir Turkey

4. Department of ParasitologyManisa Celal Bayar University Manisa Turkey

Funder

Ege Üniversitesi

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Reference58 articles.

1. WHO Leishmaniasis Fact Sheet Updated March2019.https://www.who.int/en/news‐room/fact‐sheets/detail/leishmaniasis(accessed: October 2019)

2. DNDi Leishmaniasis Fact Sheet https://www.dndi.org/wp‐content/uploads/2019/09/Factsheet2019_Leishmaniasis.pdf(accessed: October 2019)

3. Leishmaniasis in Turkey: first clinical isolation ofLeishmania majorfrom 18 autochthonous cases of cutaneous leishmaniasis in four geographical regions

4. Characterization of the Antimonial Antileishmanial Agent Meglumine Antimonate (Glucantime)

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