Synthesis and Selective Inhibitory Activity Against Human COX-1 of Novel 1-(4-Substituted-thiazol-2-yl)-3,5-di(hetero)aryl-pyrazoline Derivatives
Author:
Publisher
Wiley
Subject
Drug Discovery,Pharmaceutical Science
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ardp.201200249/fullpdf
Reference17 articles.
1. The COXIB Experience: A Look in the Rearview Mirror
2. Effects of cyclooxygenase inhibition on the gastrointestinal tract
3. Selective COX-1 Inhibition: A Therapeutic Target to be Reconsidered
4. 2-Amino-5-thiazolyl motif: A novel scaffold for designing anti-inflammatory agents of diverse structures
5. Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors
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